THE MOBILIZE BOSTON STUDY: DESIGN AND METHODS OF A PROSPECTIVE COHORT STUDY OF NOVEL RISK FACTORS FOR FALLS IN AN OLDER POPULATION

The MOBILIZE Boston Study: Design and methods of a prospective cohort study of novel risk factors for falls in an older population

Abstract Background Falls are the sixth leading cause of death in elderly people in the U.S.Despite progress in understanding risk factors for falls, many suspected risk factors have not been adequately studied.Putative risk factors for falls such as pain, reductions in cerebral blood flow, somatosensory deficits, and foot disorders are poorly unde

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Prickle isoforms determine handedness of helical morphogenesis

Subcellular asymmetry directed by the planar cell polarity (PCP) signaling pathway orients numerous morphogenetic events in both invertebrates and vertebrates.Here, we describe a morphogenetic movement in which the intertwined socket and shaft cells of the Drosophila anterior wing margin Lip Crayon mechanosensory bristles undergo PCP-directed apica

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